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糖尿病研究センター

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研究業績

2018年(平成30年)

  • The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.
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    Kobayashi M, Ohsugi M, Sasako T, Awazawa M, Umehara T, Iwane A, Kobayashi N, Okazaki Y, Kubota N, Suzuki R, Waki H, Horiuchi K, Hamakubo T, Kodama T, Aoe S, Tobe K, Kadowaki T, Ueki K.
    Molecular and Cellular Biology. 2018 Jul 30;38(16). pii: e00116-18. Print 2018 Aug 15.
    doi: 10.1128/MCB.00116-18.
  • Guidelines for clinical evaluation of chronic kidney disease : AMED research on regulatory science of pharmaceuticals and medical devices.
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    Kanda E, Kashihara N, Matsushita K, Usui T, Okada H, Iseki K, Mikami K, Tanaka T, Wada T, Watada H, Ueki K, Nangaku M; Research Working Group for Establishing Guidelines for Clinical Evaluation of Chronic Kidney Disease.
    Clinical and Experimental Nephrology. 2018 Jul 13. [Epub ahead of print]
    doi: 10.1007/s10157-018-1615-x.
  • Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients.
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    Enooku K, Kondo M, Fujiwara N, Sasako T, Shibahara J, Kado A, Okushin K, Fujinaga H, Tsutsumi T, Nakagomi R, Minami T, Sato M, Nakagawa H, Kondo Y, Asaoka Y, Tateishi R, Ueki K, Ikeda H, Yoshida H, Moriya K, Yotsuyanagi H, Kadowaki T, Fukayama M, Koike K.
    Journal of Gastroenterology. 2018 May 10. [Epub ahead of print]
    doi: 10.1007/s00535-018-1472-0.
  • Hepatocellular carcinoma as a leading cause of cancer-related deaths in Japanese type 2 diabetes mellitus patients.
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    Shima T, Uto H, Ueki K, Kohgo Y, Yasui K, Nakamura N, Nakatou T, Takamura T, Kawata S, Notsumata K, Sakai K, Tateishi R, Okanoue T.
    Journal of Gastroenterology. 2018 Jul 13. [Epub ahead of print]
    doi: 10.1007/s00535-018-1494-7.

2017年(平成29年)

  • A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle
    Awazawa M, Gabel P, Tsaousidou E, Nolte H, Krüger M, Schmitz J, Ackermann PJ, Brandt C, Altmüller J, Motameny S, Wunderlich FT, Kornfeld JW, Blüher M, Brüning JC.
    Nature Medicine. 2017 Dec;23(12):1466-1473. Epub 2017 Nov 6.
    doi: 10.1038/nm.4420.
  • Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (JDOIT3): an openlabel, randomised controlled trial
    Ueki K, Sasako T, Okazaki Y, Kato M, Okahata S, Katsuyama H, Haraguchi M, Morita A, Ohashi K, Hara K, Morise A, Izumi K, Ishizuka N, Ohashi Y, Noda M, Kadowaki T; JDOIT3 Study Group
    Lancet Diabetes Endocrinol. 2017 Dec;5(12):951-964 Epub 2017 Oct 24.
    doi: 10.1016/S2213-8587(17)30327-3.
  • CD206(+) M2like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors
    Nawaz A, Aminuddin A, Kado T, Takikawa A, Yamamoto S, Tsuneyama K, Igarashi Y, Ikutani M, Nishida Y, Nagai Y, Takatsu K, Imura J, Sasahara M, Okazaki Y, Ueki K, Okamura T, Tokuyama K, Ando A, Matsumoto M, Mori H, Nakagawa T, Kobayashi N, et al.
    Nature Communications. 2017 Aug 18;8(1):286.
    doi: 10.1038/s41467-017-00231-1.
  • Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney
    Sasaki M, Sasako T, Kubota N, Sakurai Y, Takamoto I, Kubota T, Inagi R, Seki G, Goto M, Ueki K, Nangaku M, Jomori T, Kadowaki T
    Diabetes. 2017 Sep;66(9):2339-2350 2017 Jun 19.
    doi: 10.2337/db16-1602.
  • Causes of death in Japanese patients with diabetes based on the results of a survey of 45,708 cases during 2001-2010: Report of the Committee on Causes of Death in Diabetes Mellitus
    Nakamura J, Kamiya H, Haneda M, Inagaki N, Tanizawa Y, Araki E, Ueki K, Nakayama T
    Journal of Diabetes Investigation. 2017 May;8(3):397-410. Epub 2017 Mar 27.
    doi: 10.1111/jdi.12645.
  • Psychological and behavioural patterns of stigma among patients with type 2 diabetes: a cross-sectional study
    Kato A, Fujimaki Y, Fujimori S, Isogawa A, Onishi Y, Suzuki R, Yamauchi T, Ueki K, Kadowaki T, Hashimoto H
    BMJ Open. 2017 Mar 29;7(3):e013425.
    doi: 10.1136/bmjopen-2016-013425.
  • New glycemic targets for patients with diabetes from the Japan Diabetes Society
    Araki E, Haneda M, Kasuga M, Nishikawa T, Kondo T, Ueki K, Kadowaki T
    Journal of Diabetes Investigation. 2017 Jan;8(1):123-125. Epub 2016 Dec 9.
    doi: 10.1111/jdi.12600.

2016年(平成28年)

  • Factors Associated With Callus in Patients with Diabetes, Focused on Plantar Shear Stress During Gait
    Hamatani M, Mori T, Oe M, Noguchi H, Takehara K, Amemiya A, Ohashi Y, Ueki K, Kadowaki T, Sanada H
    Journal of Diabetes Science and Technology. 2016 Nov 1;10(6):1353-1359. Print 2016 Nov.
    doi: 10.1177/1932296816648164
  • Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity
    Kubota N, Kubota T, Kajiwara E, Iwamura T, Kumagai H, Watanabe T, Inoue M, Takamoto I, Sasako T, Kumagai K, Kohjima M, Nakamuta M, Moroi M, Sugi K, Noda T, Terauchi Y, Ueki K, Kadowaki T
    Nature Communications. 2016 Oct 6;7:12977
    doi: 10.1038/ncomms12977.
  • Pioglitazone Ameliorates Smooth Muscle Cell Proliferation in Cuff-Induced Neointimal Formation by Both Adiponectin-Dependent and -Independent Pathways
    Kubota T, Kubota N, Sato H, Inoue M, Kumagai H, Iwamura T, Takamoto I, Kobayashi T, Moroi M, Terauchi Y, Tobe K, Ueki K, Kadowaki T
    Scientific Reports. 2016 Oct 5;6:34707
    doi: 10.1038/srep34707.
  • A qualitative study on the impact of internalized stigma on type 2 diabetes self-management
    Kato A, Fujimaki Y, Fujimori S, Izumida Y, Suzuki R, Ueki K, Kadowaki T, Hashimoto H
    Patient Education and Counseling. 2016 Jul;99(7):1233-1239. Epub 2016 Feb 8.
    doi: 10.1016/j.pec.2016.02.002.
  • Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report
    Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H
    Cancer Sciense. 2016 Mar;107(3):369-71.
    doi: 10.1111/cas.12889.
  • Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice
    Obata A, Kubota N, Kubota T, Iwamoto M, Sato H, Sakurai Y, Takamoto I, Katsuyama H, Suzuki Y, Fukazawa M, Ikeda S, Iwayama K, Tokuyama K, Ueki K, Kadowaki T
    Endocrinology. 2016 Mar;157(3):1029-42 Epub 2015 Dec 29.
    doi: 10.1210/en.2015-1588.
  • Design of and rationale for the Japan Diabetes Optimal Integrated Treatment study for 3 major risk factors of cardiovascular diseases (J-DOIT3): a multicenter, open-label, randomized, parallel-group trial
    Ueki K, Sasako T, Kato M, Okazaki Y, Okahata S, Katsuyama H, Haraguchi M, Morita A, Ohashi K, Hara K, Morise A, Izumi K, Ohashi Y, Noda M, Kadowaki T, J-DOIT3 Study Group
    BMJ Open Diabetes Research & Care. 2016 Jan 25;4(1):e000123. eCollection 2016.
    doi: 10.1136/bmjdrc-2015-000123.
  • Association between self-stigma and self-care behaviors in patients with type 2 diabetes: a cross-sectional study
    Kato A, Fujimaki Y, Fujimori S, Isogawa A, Onishi Y, Suzuki R, Yamauchi T, Ueki K, Kadowaki T, Hashimoto H
    BMJ Open Diabetes Research & Care. 2016 Jan 5;4(1):e000156 eCollection 2016.
    doi: 10.1136/bmjdrc-2015-000156.

2015年(平成27年)

  • A Large-scale, Observational Study to Investigate the Current Status of Diabetic Complications and Their Prevention in Japan: Research Outline and Baseline Data for Type 1 Diabetes - JDCP study 2
    Tajima N, Nishimura R, Izumi K, Hayashino Y, Origasa H, Noda M, Ueki K
    Journal of the Japan Diabetes Society. 6(4): 243-251, 2015
    doi: org/10.11213/tonyobyo.58.426
  • Comparison of Gait Features Between Feet With Callus or Corns and Normal Feet Using Motion Sensors in People With Diabetes and People Without Diabetes
    Amemiya A, Noguchi H, Oe M, Ohashi Y, Takehara K, Ueki K, Kadowaki T, Sanada H, Mori T
    Journal of Diabetes Science and Technology. 2015 Nov 17;10(2):614-5.
    doi: 10.1177/1932296815616135.
  • Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity
    Okada-Iwabu M, Iwabu M, Ueki K, Yamauchi T, Kadowaki T
    Diabetes & Metabolism Journal. 2015 Oct;39(5):363-72. Epub 2015 Oct 22.
    doi: 10.4093/dmj.2015.39.5.363.
  • A case of insulin allergy successfully managed using multihexamer-forming insulin degludec combined with liraglutide
    Fujishiro M, Izumida Y, Takemiya S, Kuwano Y, Takamoto I, Suzuki R, Yamauchi T, Ueki K, Kadowaki T
    Diabetic Medicine. 2016 Nov;33(11):e26-e29
    doi: 10.1111/dme.12998.
  • A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice
    Shiomi Y, Yamauchi T, Iwabu M, Okada-Iwabu M, Nakayama R, Orikawa Y, Yoshioka Y, Tanaka K, Ueki K, Kadowaki T
    Journal of Biological Chemstry. 2015 Jun 5;290(23):14567-81. Epub 2015 Apr 23.
    doi: 10.1074/jbc.M114.622191.
  • Association between Washing Residue on the Feet and Tinea Pedis in Diabetic Patients
    Takehara K, Amemiya A, Mugita Y, Tsunemi Y, Seko Y, Ohashi Y, Ueki K, Kadowaki T, Oe M, Nagase T, Ikeda M, Sanada H
    Nursing Research and Practice. 2015;2015:872678. 2015 Feb 22.
    doi: 10.1155/2015/872678.