2019年（平成31年）

• Changes in the quality of diabetes care in Japan between 2007 and 2015: A repeated cross-sectional study using claims data
  
  

  Hirokazu Tanaka, Takehiro Sugiyama, Noriko Ihana-Sugiyama, Kohjiro Ueki, Yasuki Kobayashi, Mitsuru Ohsugi.
  Diabetes Research and Clinical Practice. March 2019
  doi: https://doi.org/10.1016/j.diabres.2019.02.001
• Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism
  Takayoshi Sasako, Mitsuru Ohsugi, Naoto Kubota, Shinsuke Itoh, Yukiko Okazaki, Ai Terai, Tetsuya Kubota, Satoshi Yamashita, Kunio Nakatsukasa, Takumi Kamura, Kaito Iwayama, Kumpei Tokuyama, Hiroshi Kiyonari, Yasuhide Furuta, Junji Shibahara, Masashi Fukayama, Kenichiro Enooku, Kazuya Okushin, Takeya Tsutsumi, Ryosuke Tateishi, Kazuyuki Tobe, Hiroshi Asahara, Kazuhiko Koike, Takashi Kadowaki, and Kohjiro Ueki.
  Nature Communications. 2019 Feb. 27
  doi: 10.1038/s41467-019-08591-6

2018年（平成30年）

• PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes.
  Yano H, Sakai M, Matsukawa T, Yagi T, Naganuma T, Mitsushima M, Iida S, Inaba Y, Inoue H, Unoki-Kubota H, Kaburagi Y, Asahara SI, Kido Y, Minami S, Kasuga M, Matsumoto M.
  Scientific Reports.. 2018 Sep 24;8(1):14290.
  doi: 10.1038/s41598-018-32575-z.
• Urinary afamin levels are associated with the progression of diabetic nephropathy
  
  

  Kaburagi Y, Takahashi E, Kajio H, Yamashita S, Yamamoto-Honda R, Shiga T, Okumura A, Goto A, Fukazawa Y, Seki N, Tobe K, Matsumoto M, Noda M, UnokiKubota H
  Diabetes Research and Clinical Practice. 2018 Mar 6. pii: S0168-8227(17)31788-6. [Epub ahead of print]
  doi: 10.1016/j.diabres.2018.02.034.
• The Effects of Laparoscopic Sleeve Gastrectomy with Duodenojejunal Bypass on Japanese Patients with BMI < 35 kg/m2 on Type 2 Diabetes Mellitus and the Prediction of Successful Glycemic Control
  
  

  Seki Y, Kasama K, Yasuda K, Yokoyama R, Porciuncula JP, Kurokawa Y
  Obesity Surgery. 2018 Aug;28(8):2429-2438.
  doi: 10.1007/s11695-018-3179-y.
• Metabolic surgery for inadequately controlled type 2 diabetes in nonseverely obese Japanese: a prospective, single-center study
  
  

  Seki Y, Kasama K, Yasuda K, Kikkawa E, Watanabe N, Kurokawa Y
  Surgery for Obesity and Related Diseases. 2018 Jul;14(7):978-985. Epub 2018 Mar 21.
  doi: 10.1016/j.soard.2018.03.016.
• The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.
  
  

  Kobayashi M, Ohsugi M, Sasako T, Awazawa M, Umehara T, Iwane A, Kobayashi N, Okazaki Y, Kubota N, Suzuki R, Waki H, Horiuchi K, Hamakubo T, Kodama T, Aoe S, Tobe K, Kadowaki T, Ueki K.
  Molecular and Cellular Biology. 2018 Jul 30;38(16). pii: e00116-18. Print 2018 Aug 15.
  doi: 10.1128/MCB.00116-18.
• Thioacetamideinduced hepatic fibrosis in the common marmoset
  
  

  Inoue T, Ishizaka Y, Sasaki E, Lu J, Mineshige T, Yanase M, Sasaki E, Shimoda M.
  Experimental Animals. 2018 Jul 30;67(3):321-327. Epub 2018 Mar 22.
  doi: 10.1538/expanim.17-0156.
• Guidelines for clinical evaluation of chronic kidney disease : AMED research on regulatory science of pharmaceuticals and medical devices.
  
  

  Kanda E, Kashihara N, Matsushita K, Usui T, Okada H, Iseki K, Mikami K, Tanaka T, Wada T, Watada H, Ueki K, Nangaku M; Research Working Group for Establishing Guidelines for Clinical Evaluation of Chronic Kidney Disease.
  Clinical and Experimental Nephrology. 2018 Jul 13. [Epub ahead of print]
  doi: 10.1007/s10157-018-1615-x.
• Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients.
  
  

  Enooku K, Kondo M, Fujiwara N, Sasako T, Shibahara J, Kado A, Okushin K, Fujinaga H, Tsutsumi T, Nakagomi R, Minami T, Sato M, Nakagawa H, Kondo Y, Asaoka Y, Tateishi R, Ueki K, Ikeda H, Yoshida H, Moriya K, Yotsuyanagi H, Kadowaki T, Fukayama M, Koike K.
  Journal of Gastroenterology. 2018 May 10. [Epub ahead of print]
  doi: 10.1007/s00535-018-1472-0.
• Hepatocellular carcinoma as a leading cause of cancer-related deaths in Japanese type 2 diabetes mellitus patients.
  
  

  Shima T, Uto H, Ueki K, Kohgo Y, Yasui K, Nakamura N, Nakatou T, Takamura T, Kawata S, Notsumata K, Sakai K, Tateishi R, Okanoue T.
  Journal of Gastroenterology. 2018 Jul 13. [Epub ahead of print]
  doi: 10.1007/s00535-018-1494-7.
• Bariatric and metabolic surgery in Asia: Where are we, and where are we going?
  
  

  Yasuda K
  Journal of Diabetes Investigation. 2018 Jul 6. Epub ahead of print
  doi: 10.1111/jdi.12893.
• Characteristics and clinical course of type 1 diabetes mellitus related to anti-programmed cell death-1 therapy
  
  

  Yamaguchi-Baden M, Imagawa A, Abiru N, Awata T, Ikegami H, Uchigata Y, Oikawa Y, Osawa H, Kajio H, Kawasaki E, Kawabata Y, Kozawa J, Shimada A, Takahashi K, Tanaka S, Chujo D, Fukui T, Miura J, Yasuda K, Yasuda H, Kobayashi T, Hanafusa T, for the consultation of the Japan Diabetes Society Committee on Type 1 Diabetes Mellitus Research.
  Diabetology International. published on-line.
  doi: 10.1007/s13340-018-0362-2.
• Predictive performance of a genetic risk score using 11 susceptibility alleles for the incidence of Type 2 diabetes in a general Japanese population: a nested case-control study
  
  

  Goto A, Noda M, Goto M, Yasuda K, Mizoue T, Yamaji T, Sawada N, Iwasaki M, Inoue M, Tsugane S, for the JPHC Study Group.
  Diabetic Medicine. 2018 May;35(5):602-611. Epub 2018 Mar 12.
  doi: 10.1111/dme.13602.
• Optical clearing of the pancreas for visualization of mature β-cells and vessels in mice
  
  

  Nishimura W, Sakaue-Sawano A, Takahashi S, Miyawaki A, Yasuda K, Noda Y
  Journal Islets. 2018 May 4;10(3):e1451282. Epub 2018 Apr 4.
  doi: 10.1080/19382014.2018.1451282.
• Diffusion-weighted magnetic resonance imaging in the pancreas of fulminant type 1 diabetes
  Tokunaga A, Imagawa A, Nishio H, Hayata S, Shimomura I, Abiru N, Awata T, Ikegami H, Uchigata Y, Oikawa Y, Osawa H, Kajio H, Kawasaki E, Kawabata Y, Kozawa J, Shimada A, Takahashi K, Tanaka S, Chujo D, Fukui T, Miura J, Yasuda K, Yasuda H, Kobayashi T, Hanafusa T, for the consultation of the Japan Diabetes Society Committee on Type 1 Diabetes Mellitus Research.
  Diabetology International. published on-line.
  doi: 10.1007/s13340-018-0355-1.
• A type 2 diabetes-associated SNP in KCNQ1 (rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a, potentially affecting CDKN1C expression
  
  

  Hiramoto M, Udagawa H, Ishibashi N, Takahashi E, Kaburagi Y, Miyazawa K, Funahashi N, Nammo T, Yasuda K
  International Journal of Molecular Medicine. 2018 Feb;41(2):717-728. Epub 2017 Nov 20.
  doi: 10.3892/ijmm.2017.3273.
• Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein
  Watanabe H, Inaba Y, Kimura K, Matsumoto M, Kaneko S, Kasuga M, Inoue H
  Nature Communicationsvolume. 2018 Jan 2;9(1):30.
  doi: 10.1038/s41467-017-02537-6.

2017年（平成29年）

• Circulating ferritin concentrations are differentially associated with serum adipokine concentrations in Japanese men and premenopausal women
  
  

  Kimura Y, Yasuda K, Kurotani K, Akter S, Kashino I, Hayabuchi H, Sato M, Mizoue T
  European Journal of Nutrition. 2017 Dec;56(8):2497-2505. Epub 2016 Aug 2.
  doi: 10.1007/s00394-016-1285-y.
• Circadian clock regulates hepatic polyploidy by modulating Mkp1Erk1/2 signaling pathway
  Chao HW, Doi M, Fustin JM, Chen H, Murase K, Maeda Y, Hayashi H, Tanaka R, Sugawa M, Mizukuchi N, Yamaguchi Y, Yasunaga JI, Matsuoka M, Sakai M, Matsumoto M, Hamada S, Okamura H
  Nature Communications. 2017 Dec 21;8(1):2238.
  doi: 10.1038/s41467-017-02207-7.
• A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle
  Awazawa M, Gabel P, Tsaousidou E, Nolte H, Krüger M, Schmitz J, Ackermann PJ, Brandt C, Altmüller J, Motameny S, Wunderlich FT, Kornfeld JW, Blüher M, Brüning JC.
  Nature Medicine. 2017 Dec;23(12):1466-1473. Epub 2017 Nov 6.
  doi: 10.1038/nm.4420.
• Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (JDOIT3): an openlabel, randomised controlled trial
  
  

  Ueki K, Sasako T, Okazaki Y, Kato M, Okahata S, Katsuyama H, Haraguchi M, Morita A, Ohashi K, Hara K, Morise A, Izumi K, Ishizuka N, Ohashi Y, Noda M, Kadowaki T; JDOIT3 Study Group
  Lancet Diabetes Endocrinol. 2017 Dec;5(12):951-964 Epub 2017 Oct 24.
  doi: 10.1016/S2213-8587(17)30327-3.
• Pleckstrin homologylike domain family A, member 3 (PHLDA3) deficiency improves islets engraftment through the suppression of hypoxic damage
  Sakata N, Yamaguchi Y, Chen Y, Shimoda M, Yoshimatsu G, Unno M, Sumi S, Ohki R.
  PLoS One. 2017 Nov 9;12(11):e0187927. eCollection 2017.
  doi: 10.1371/journal.pone.0187927.
• Methods for Microencapsulated Porcine Islet Production
  Shimoda M, Matsumoto S.
  Methods in Molecular Biology. 2017;1479:347-356.
  doi: 10.1007/978-1-4939-6364-5_26.
• Microencapsulation in Clinical Islet Xenotransplantation
  Shimoda M, Matsumoto S.
  Methods in Molecular Biology. 1479:335-345, 2017.
  doi: 10.1007/978-1-4939-6364-5_25.
• Alleviation of lipopolysaccharide/dgalactosamineinduced liver injury in leukocyte cellderived chemotaxin 2 deficient mice
  Okumura A, Saito T, Tobiume M, Hashimoto Y, Sato Y, Umeyama T, Nagi M, Tanabe K, UnokiKubota H, Kaburagi Y, Hasegawa H, Miyazaki Y, Yamagoe S
  Biochemistry and Biophysics Reports. 2017 Oct 13;12:166-171. eCollection 2017 Dec.
  doi: 10.1016/j.bbrep.2017.09.011.
• Proteomic analysis of serum biomarkers for prediabetes using the Long-Evans Agouti rat, a spontaneous animal model of type 2 diabetes mellitus
  Takahashi E, Unoki-Kubota H, Shimizu Y, Okamura T, Iwata W, Kajio H, Yamamoto-Honda R, Shiga T, Yamashita S, Tobe K, Okumura A, Matsumoto M, Yasuda K, Noda M, Kaburagi Y
  Journal of Diabetes Investigation. 2017 Sep;8(5):661-671. Epub 2017 Mar 27.
  doi: 10.1111/jdi.12638.
• CD206(+) M2like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors
  Nawaz A, Aminuddin A, Kado T, Takikawa A, Yamamoto S, Tsuneyama K, Igarashi Y, Ikutani M, Nishida Y, Nagai Y, Takatsu K, Imura J, Sasahara M, Okazaki Y, Ueki K, Okamura T, Tokuyama K, Ando A, Matsumoto M, Mori H, Nakagawa T, Kobayashi N, et al.
  Nature Communications. 2017 Aug 18;8(1):286.
  doi: 10.1038/s41467-017-00231-1.
• Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney
  
  

  Sasaki M, Sasako T, Kubota N, Sakurai Y, Takamoto I, Kubota T, Inagi R, Seki G, Goto M, Ueki K, Nangaku M, Jomori T, Kadowaki T
  Diabetes. 2017 Sep;66(9):2339-2350 2017 Jun 19.
  doi: 10.2337/db16-1602.
• Causes of death in Japanese patients with diabetes based on the results of a survey of 45,708 cases during 2001-2010: Report of the Committee on Causes of Death in Diabetes Mellitus
  
  

  Nakamura J, Kamiya H, Haneda M, Inagaki N, Tanizawa Y, Araki E, Ueki K, Nakayama T
  Journal of Diabetes Investigation. 2017 May;8(3):397-410. Epub 2017 Mar 27.
  doi: 10.1111/jdi.12645.
• Even and oddchain saturated fatty acids in serum phospholipids are differentially associated with adipokines.
  Kurotani K, Sato M, Yasuda K, Kashima K, Tanaka S, Hayashi T, Shirouchi B, Akter S, Kashino I, Hayabuchi H, Mizoue T.
  PLoS One. 2017 May 26;12(5):e0178192. eCollection 2017.
  doi: 10.1371/journal.pone.0178192.
• Plasma adiponectin levels, ADIPOQ variants, and incidence of type 2 diabetes: A nested casecontrol study
  Goto A, Noda M, Goto M, Yasuda K, Mizoue T, Yamaji T, Sawada N, Iwasaki M, Inoue M, Tsugane S; JPHC Study Group
  Diabetes Research and Clinical Practice. 2017 May;127:254-264. Epub 2017 Mar 24.
  doi: 10.1016/j.diabres.2017.03.020.
• Psychological and behavioural patterns of stigma among patients with type 2 diabetes: a cross-sectional study
  Kato A, Fujimaki Y, Fujimori S, Isogawa A, Onishi Y, Suzuki R, Yamauchi T, Ueki K, Kadowaki T, Hashimoto H
  BMJ Open. 2017 Mar 29;7(3):e013425.
  doi: 10.1136/bmjopen-2016-013425.
• Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: Comparison with hepatitis virus-related carcinogenesis
  
  

  Kuramoto J, Arai E, Tian Y, Funahashi N, Hiramoto M, Nammo T, Nozaki Y, Takahashi Y, Ito N, Shibuya A, Ojima H, Sukeda A, Seki Y, Kasama K, Yasuda K, Kanai Y
  Carcinogenesis. 2017 Mar 1;38(3):261-270.
  doi: 10.1093/carcin/bgx005.
• Efficient generation of functional pancreatic β-cells from human induced pluripotent stem cells
  Yabe SG, Fukuda S, Takeda F, Nashiro K, Shimoda M, Okochi H.
  Journal of Diabetes. 2017 Feb;9(2):168-179. Epub 2016 May 31.
  doi: 10.1111/1753-0407.12400.
• Clinical features of distinct diabetes in which anti-glutamic acid decarboxylase antibody seroconverted during a clinical course of type 2 diabetes: a nationwide survey in Japan.
  
  

  Oikawa Y, Shimada A, Awata T, Fukui T, Ikegami H, Imagawa A, Kajio H, Kawabata Y, Kawasaki E, Miura J, Osawa H, Takahashi K, Tanaka S, Uchigata Y, Yasuda H, Yasuda K, Hanafusa T, Kobayashi T.
  Diabetology International. 8(3):306-315, 2017.
  doi: 10.1007/s13340-017-0312-4.
• Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-Induced, Nonalcoholic Fatty Liver Disease
  
  

  Watanabe H, Inaba Y, Kimura K, Asahara SI, Kido Y, Matsumoto M, Motoyama T, Tachibana N, Kaneko S, Kohno M, Inoue H
  The Journal of Nutrition. 2017 Jan;147(1):52-60. Epub 2016 Nov 30
  doi: 10.3945/jn.116.231662.
• Biosci Trends. A novel angiogenic peptide, ΔADT: A truncated adrenotensin peptide revealed by secretory peptidome analysis of human
  Okumura A, Takahashi E, Unoki-Kubota H, Kaburagi Y
  BioScience Trends. 2017 Jan 16;10(6):500-506. Epub 2016 Nov 13.
  doi: 10.5582/bst.2016.01189.
• New glycemic targets for patients with diabetes from the Japan Diabetes Society
  
  

  Araki E, Haneda M, Kasuga M, Nishikawa T, Kondo T, Ueki K, Kadowaki T
  Journal of Diabetes Investigation. 2017 Jan;8(1):123-125. Epub 2016 Dec 9.
  doi: 10.1111/jdi.12600.

2016年（平成28年）

• Reduced serum level of leukocyte cell-derived chemotaxin 2 is associated with the presence of diabetic retinopathy
  Okumura A, Unoki-Kubota H, Yoshida-Hata N, Yamamoto-Honda R, Yamashita S, Iwata M, Tobe K, Kajio H, Noda M, Katai N, Yamagoe S, Kaburagi Y
  Clinica Chimica Acta. 2016 Dec 1;463:145-149. Epub 2016 Oct 29.
  doi: 10.1016/j.cca.2016.10.031.
• The GCN5-CITED2-PKA module controls glucose metabolism through a cAMP-induced substrate switch
  Sakai M, Tsujimura-Hayakawa T, Yagi T, Yano H, Mitsushima M, Unoki-Kubota H, Kaburagi Y, Inoue H, Kido Y, Kasuga M, Matsumoto M
  Nature Communications. 2016 Nov 22;7:13147.
  doi: 10.1038/ncomms13147.
• Factors Associated With Callus in Patients with Diabetes, Focused on Plantar Shear Stress During Gait
  Hamatani M, Mori T, Oe M, Noguchi H, Takehara K, Amemiya A, Ohashi Y, Ueki K, Kadowaki T, Sanada H
  Journal of Diabetes Science and Technology. 2016 Nov 1;10(6):1353-1359. Print 2016 Nov.
  doi: 10.1177/1932296816648164
• Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity
  Kubota N, Kubota T, Kajiwara E, Iwamura T, Kumagai H, Watanabe T, Inoue M, Takamoto I, Sasako T, Kumagai K, Kohjima M, Nakamuta M, Moroi M, Sugi K, Noda T, Terauchi Y, Ueki K, Kadowaki T
  Nature Communications. 2016 Oct 6;7:12977
  doi: 10.1038/ncomms12977.
• Pioglitazone Ameliorates Smooth Muscle Cell Proliferation in Cuff-Induced Neointimal Formation by Both Adiponectin-Dependent and -Independent Pathways
  Kubota T, Kubota N, Sato H, Inoue M, Kumagai H, Iwamura T, Takamoto I, Kobayashi T, Moroi M, Terauchi Y, Tobe K, Ueki K, Kadowaki T
  Scientific Reports. 2016 Oct 5;6:34707
  doi: 10.1038/srep34707.
• Risk factors of sudden death and cardiac arrest at the onset of fulminant type 1 diabetes mellitus
  Yamaguchi-Baden M, Imagawa A, Iwahashi H, Shimomura I, Awata T, Ikegami H, Uchigata Y, Osawa H, Kajio H, Kawasaki E, Kawabata Y, Shimada A, Takahashi K, Tanaka S, Yasuda K, Yasuda H, Kobayashi T, Hanafusa T, for the consultation of the Japan Diabetes Society Committee on Type 1 Diabetes Mellitus Research.
  Diabetology International. 2016, Vol.7, No.3, 281-288.
  doi: 10.1007/s13340-015-0247-6.
• HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance
  Takikawa A, Mahmood A, Nawaz A, Kado T, Okabe K, Yamamoto S, Aminuddin A, Senda S, Tsuneyama K, Ikutani M, Watanabe Y, Igarashi Y, Nagai Y, Takatsu K, Koizumi K, Imura J, Goda N, Sasahara M, Matsumoto M, Saeki K, Nakagawa T, Fujisaka S, Usui I, Tobe K
  Diabetes. 2016 Dec;65(12):3649-3659. Epub 2016 Sep 13.
  doi:
• Crystal Structure of Human Leukocyte Cell-derived Chemotaxin 2 (LECT2) Reveals a Mechanistic Basis of Functional Evolution in a Mammalian Protein with an M23 Metalloendopeptidase Fold
  Zheng H, Miyakawa T, Sawano Y, Asano A, Okumura A, Yamagoe S, Tanokura M
  Journal of Biological Chemistry. 2016 Aug 12;291(33):17133-42. Epub 2016 Jun 22.
  doi: 10.1074/jbc.M116.720375.
• p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress.
  Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K.
  Cell Stem Cell. 2016 Aug 4;19(2):192-204. Epub 2016 Jun 23.
  doi: 10.1016/j.stem.2016.05.013.
• A qualitative study on the impact of internalized stigma on type 2 diabetes self-management
  Kato A, Fujimaki Y, Fujimori S, Izumida Y, Suzuki R, Ueki K, Kadowaki T, Hashimoto H
  Patient Education and Counseling. 2016 Jul;99(7):1233-1239. Epub 2016 Feb 8.
  doi: 10.1016/j.pec.2016.02.002.
• Clinical and genetic characteristics of non-insulin-requiring glutamic acid decarboxylase (GAD) autoantibody-positive diabetes: a nation-wide survey in Japan
  Yasui J, Kawasaki E, Tanaka S, Awata T, Ikegami H, Imagawa A, Uchigata R, Osawa H, Kajio H, Kawabata Y, Shimada A, Takahashi K, Yasuda K, Yasuda H, Hanafusa T, Kobayashi T, for the consultation of the Japan Diabetes Society Committee on type 1 Diabetes Mellitus Research.
  PLoS One. 2016 May 13;11(5):e0155643. eCollection 2016.
  doi: 10.1371/journal.pone.0155643.
• Ultrasound-Targeted Microbubble Destruction (UTMD): Towards a new strategy for diabetes treatment?
  Mozafari M, Shimoda M, Urbanska AM, Laurent S.
  Drug Discovery Today. 2016 Apr;21(4):540-3. Epub 2015 Nov 29.
  doi: 10.1016/j.drudis.2015.11.010.
• Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report
  Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H
  Cancer Sciense. 2016 Mar;107(3):369-71.
  doi: 10.1111/cas.12889.
• Central Insulin Action Activates Kupffer Cells by Suppressing Hepatic Vagal Activation via the Nicotinic Alpha 7 Acetylcholine Receptor
  Kimura K, Tanida M, Nagata N, Inaba Y, Watanabe H, Nagashimada M, Ota T, Asahara S, Kido Y, Matsumoto M, Toshinai K, Nakazato M, Shibamoto T, Kaneko S, Kasuga M, Inoue H
  Cell Reports. 2016 Mar 15;14(10):2362-74. Epub 2016 Mar 3.
  doi: 10.1016/j.celrep.2016.02.032.
• Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice
  Obata A, Kubota N, Kubota T, Iwamoto M, Sato H, Sakurai Y, Takamoto I, Katsuyama H, Suzuki Y, Fukazawa M, Ikeda S, Iwayama K, Tokuyama K, Ueki K, Kadowaki T
  Endocrinology. 2016 Mar;157(3):1029-42 Epub 2015 Dec 29.
  doi: 10.1210/en.2015-1588.
• Hepatocyte β-Klotho regulates lipid homeostasis but not body weight in mice
  Kobayashi K, Tanaka T, Okada S, Morimoto Y, Matsumura S, Manio MC, Inoue K, Kimura K, Yagi T, Saito Y, Fushiki T, Inoue H, Matsumoto M, Nabeshima Y
  The FASEB Journal. 2016 Feb;30(2):849-62. Epub 2015 Oct 29.
  doi: 10.1096/fj.15-274449.
• Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
  Imamura M, Takahashi A, Yamauchi T, Hara K, Yasuda K, Grarup N, Zhao W, Wang X, Huerta-Chagoya A, Hu C, Moon S, Long J, Kwak SH, Rasheed A, Saxena R, Ma RC, Okada Y, Iwata M, Hosoe J, Shojima N, Iwasaki M, Fujita H, Suzuki K, Danesh J, J?rgensen T, J?rgensen ME, Witte DR, Brandslund I, Christensen C, Hansen T, Mercader JM, Flannick J, Moreno-Mac?as H, Burtt NP, Zhang R, Kim YJ, Zheng W, Singh JR, Tam CH, Hirose H, Maegawa H, Ito C, Kaku K, Watada H, Tanaka Y, Tobe K, Kawamori R, Kubo M, Cho YS, Chan JC, Sanghera D, Frossard P, Park KS, Shu XO, Kim BJ, Florez JC, Tusi?-Luna T, Jia W, Tai ES, Pe
  Nature Communications. 2016 Jan 28;7:10531.
  doi: 10.1038/ncomms10531.
• Design of and rationale for the Japan Diabetes Optimal Integrated Treatment study for 3 major risk factors of cardiovascular diseases (J-DOIT3): a multicenter, open-label, randomized, parallel-group trial
  Ueki K, Sasako T, Kato M, Okazaki Y, Okahata S, Katsuyama H, Haraguchi M, Morita A, Ohashi K, Hara K, Morise A, Izumi K, Ohashi Y, Noda M, Kadowaki T, J-DOIT3 Study Group
  BMJ Open Diabetes Research & Care. 2016 Jan 25;4(1):e000123. eCollection 2016.
  doi: 10.1136/bmjdrc-2015-000123.
• Association between self-stigma and self-care behaviors in patients with type 2 diabetes: a cross-sectional study
  Kato A, Fujimaki Y, Fujimori S, Isogawa A, Onishi Y, Suzuki R, Yamauchi T, Ueki K, Kadowaki T, Hashimoto H
  BMJ Open Diabetes Research & Care. 2016 Jan 5;4(1):e000156 eCollection 2016.
  doi: 10.1136/bmjdrc-2015-000156.

2015年（平成27年）

• A Large-scale, Observational Study to Investigate the Current Status of Diabetic Complications and Their Prevention in Japan: Research Outline and Baseline Data for Type 1 Diabetes - JDCP study 2
  Tajima N, Nishimura R, Izumi K, Hayashino Y, Origasa H, Noda M, Ueki K
  Journal of the Japan Diabetes Society. 6(4): 243-251, 2015
  doi: org/10.11213/tonyobyo.58.426
• Adult-onset type 1 diabetes patients display decreased IGRP-specific Tr1 cells in blood
  Chujo D, Nguyen TS, Foucat E, Blankenship D, Banchereau J, Nepom GT, Chaussabel D, Ueno H.
  Clinical Immunology. 2015 Dec;161(2):270-7. Epub 2015 Sep 2.
  doi: 10.1016/j.clim.2015.08.014.
• New categorization of human vascular endothelial cell by pro-vs anti-proliferative phenotypes
  Nishio M, Nakahara M, Sato C, Saeki Ko, Akutsu H, Umezawa A, Tobe K, Yasuda K, You A, Saeki Ku
  World Journal of Translational Medicine. Dec 12, 2015; 4(3): 88-100.
  doi: 10.5528/wjtm.v4.i3.88
• Generation and characterization of MafA-Kusabira Orange mice
  Nishimura W, Oishi H, Funahashi N, Fujiwara T, Takahashi S, Yasuda K
  Endocrine Journal. 2015;62(1):37-51. Epub 2014 Oct 1.
  doi: 10.1507/endocrj.EJ14-0296.
• Comparison of Gait Features Between Feet With Callus or Corns and Normal Feet Using Motion Sensors in People With Diabetes and People Without Diabetes
  Amemiya A, Noguchi H, Oe M, Ohashi Y, Takehara K, Ueki K, Kadowaki T, Sanada H, Mori T
  Journal of Diabetes Science and Technology. 2015 Nov 17;10(2):614-5.
  doi: 10.1177/1932296815616135.
• Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity
  Okada-Iwabu M, Iwabu M, Ueki K, Yamauchi T, Kadowaki T
  Diabetes & Metabolism Journal. 2015 Oct;39(5):363-72. Epub 2015 Oct 22.
  doi: 10.4093/dmj.2015.39.5.363.
• Compensatory Response by Late Embryonic Tubular Epithelium to the Reduction in Pancreatic Progenitors
  Nishimura W, Kapoor A, El Khattabi I, Jin W, Yasuda K, Bonner-Weir S, Sharma A
  PLoS One. 2015 Nov 5;10(11):e0142286. eCollection 2015.
  doi: 10.1371/journal.pone.0142286.
• A case of insulin allergy successfully managed using multihexamer-forming insulin degludec combined with liraglutide
  Fujishiro M, Izumida Y, Takemiya S, Kuwano Y, Takamoto I, Suzuki R, Yamauchi T, Ueki K, Kadowaki T
  Diabetic Medicine. 2016 Nov;33(11):e26-e29
  doi: 10.1111/dme.12998.
• Establishment of maturity-onset diabetes of the young-induced pluripotent stem cells from a Japanese patient
  Yabe SG, Iwasaki N, Yasuda K, Hamazaki TS, Konno M, Fukuda S, Takeda F, Kasuga M, Okochi H
  Journal of Diabetes Investigation. 2015 Sep;6(5):543-7. Epub 2015 Mar 5.
  doi: 10.1111/jdi.12334.
• A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice
  Shiomi Y, Yamauchi T, Iwabu M, Okada-Iwabu M, Nakayama R, Orikawa Y, Yoshioka Y, Tanaka K, Ueki K, Kadowaki T
  Journal of Biological Chemstry. 2015 Jun 5;290(23):14567-81. Epub 2015 Apr 23.
  doi: 10.1074/jbc.M114.622191.
• Characterization of hepatic lipid profiles in a mouse model with nonalcoholic steatohepatitis and subsequent fibrosis
  Saito K, Uebanso T, Maekawa K, Ishikawa M, Taguchi R, Nammo T, Nishimaki-Mogami T, Udagawa H, Fujii M, Shibazaki Y, Yoneyama H, Yasuda K, Saito Y
  Scientific Reports. 2015 Aug 20;5:12466.
  doi: 10.1038/srep12466.
• Demethylation of the MafB promoter in a compromised β-cell model
  Nishimura W, Ishibashi N, Eto K, Funahashi N, Udagawa H, Miki H, Oe S, Noda Y, Yasuda K
  Journal of Molecular Endocrinology. 2015 Aug;55(1):31-40. Epub 2015 Jun 24.
  doi: 10.1530/JME-15-0042.
• Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c
  Asahara S, Etoh H, Inoue H, Teruyama K, Shibutani Y, Ihara Y, Kawada Y, Bartolome A, Hashimoto N, Matsuda T, Koyanagi-Kimura M, Kanno A, Hirota Y, Hosooka T, Nagashima K, Nishimura W, Inoue H, Matsumoto M, Higgins MJ, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y
  Proceedings of the National Academy of Sciences of the United States of America. 2015 Jul 7;112(27):8332-7. Epub 2015 Jun 22.
  doi: 10.1073/pnas.1422104112.
• Association of dietary patterns with serum adipokines among Japanese: a cross-sectional study
  Kashino I, Nanri A, Kurotani K, Akter S, Yasuda K, Sato M, Hayabuchi H, Mizoue T
  Nutrition Journal. 2015 Jun 11;14:58.
  doi: 10.1186/s12937-015-0046-8.
• Comparative analysis of type 2 diabetes-associated SNP alleles identifies allele-specific DNA-binding proteins for the KCNQ1 locus
  Hiramoto M, Udagawa H, Watanabe A, Miyazawa K, Ishibashi N, Kawaguchi M, Uebanso T, Nishimura W, Nammo T, Yasuda K
  International Journal of Molecular Medicine. 2015 Jul;36(1):222-30. Epub 2015 May 8.
  doi: 10.3892/ijmm.2015.2203.
• YY1 positively regulates human UBIAD1 expression
  Funahashi N, Hirota Y, Nakagawa K, Sawada N, Watanabe M, Suhara Y, Okano T
  Biochemical and Biophysical Research Communications. 2015 May 1;460(2):238-44. Epub 2015 Mar 12.
  doi: 10.1016/j.bbrc.2015.03.018.
• Association of adulthood weight gain with circulating adipokine and insulin resistance in the Japanese population
  Kimura Y, Pham NM, Yasuda K, Nanri A, Kurotani K, Kuwahara K, Akter S, Sato M, Hayabuchi H, Mizoue T
  European Journal of Clinical Nutrition. 2015 Apr;69(4):462-6. Epub 2014 Dec 3.
  doi: 10.1038/ejcn.2014.257.
• Habitual consumption of coffee and green tea in relation to serum adipokines: a cross-sectional study
  Pham NM, Nanri A, Yasuda K, Kurotani K, Kuwahara K, Akter S, Sato M, Hayabuchi H, Mizoue T
  European Journal of Nutrition. 2015 Mar;54(2):205-14. Epub 2014 Apr 22.
  doi: 10.1007/s00394-014-0701-4.
• Diagnostic criteria for slowly progressive insulin-dependent (type 1) diabetes mellitus (SPIDDM) (2012): report by the Committee on Slowly Progressive Insulin-Dependent (Type 1) Diabetes Mellitus of the Japan Diabetes Society
  Tanaka S, Ohmori M, Awata T, Shimada A, Murao S, Maruyama T, Kamoi K, Kawasaki E, Nakanishi K, Nagata M, Fujii S, Ikegami H, Imagawa A, Uchigata Y, Okubo M, Osawa H, Kajio H, Kawaguchi A, Kawabata Y, Satoh J, Shimizu I, Takahashi K, Makino H, Iwahashi H, Miura J, Yasuda K, Hanafusa T, Kobayashi T, Committee on Type 1 Diabetes.
  Diabetology International. (2015) 6: 1.
  doi: 10.1007/s13340-014-0199-2.
• Association between Washing Residue on the Feet and Tinea Pedis in Diabetic Patients
  Takehara K, Amemiya A, Mugita Y, Tsunemi Y, Seko Y, Ohashi Y, Ueki K, Kadowaki T, Oe M, Nagase T, Ikeda M, Sanada H
  Nursing Research and Practice. 2015;2015:872678. 2015 Feb 22.
  doi: 10.1155/2015/872678.