研究業績

2018年（平成30年）

Urinary afamin levels are associated with the progression of diabetic nephropathy
Kaburagi Y, Takahashi E, Kajio H, Yamashita S, Yamamoto-Honda R, Shiga T, Okumura A, Goto A, Fukazawa Y, Seki N, Tobe K, Matsumoto M, Noda M, UnokiKubota H
Diabetes Research and Clinical Practice. 2018 Mar 6. pii: S0168-8227(17)31788-6. [Epub ahead of print]
doi: 10.1016/j.diabres.2018.02.034.

Alleviation of lipopolysaccharide/dgalactosamineinduced liver injury in leukocyte cellderived chemotaxin 2 deficient mice
Okumura A, Saito T, Tobiume M, Hashimoto Y, Sato Y, Umeyama T, Nagi M, Tanabe K, UnokiKubota H, Kaburagi Y, Hasegawa H, Miyazaki Y, Yamagoe S
Biochemistry and Biophysics Reports. 2017 Oct 13;12:166-171. eCollection 2017 Dec.
doi: 10.1016/j.bbrep.2017.09.011.
Proteomic analysis of serum biomarkers for prediabetes using the Long-Evans Agouti rat, a spontaneous animal model of type 2 diabetes mellitus
Takahashi E, Unoki-Kubota H, Shimizu Y, Okamura T, Iwata W, Kajio H, Yamamoto-Honda R, Shiga T, Yamashita S, Tobe K, Okumura A, Matsumoto M, Yasuda K, Noda M, Kaburagi Y
Journal of Diabetes Investigation. 2017 Sep;8(5):661-671. Epub 2017 Mar 27.
doi: 10.1111/jdi.12638.
Biosci Trends. A novel angiogenic peptide, ΔADT: A truncated adrenotensin peptide revealed by secretory peptidome analysis of human
Okumura A, Takahashi E, Unoki-Kubota H, Kaburagi Y
BioScience Trends. 2017 Jan 16;10(6):500-506. Epub 2016 Nov 13.
doi: 10.5582/bst.2016.01189.

Reduced serum level of leukocyte cell-derived chemotaxin 2 is associated with the presence of diabetic retinopathy
Okumura A, Unoki-Kubota H, Yoshida-Hata N, Yamamoto-Honda R, Yamashita S, Iwata M, Tobe K, Kajio H, Noda M, Katai N, Yamagoe S, Kaburagi Y
Clinica Chimica Acta. 2016 Dec 1;463:145-149. Epub 2016 Oct 29.
doi: 10.1016/j.cca.2016.10.031.
Crystal Structure of Human Leukocyte Cell-derived Chemotaxin 2 (LECT2) Reveals a Mechanistic Basis of Functional Evolution in a Mammalian Protein with an M23 Metalloendopeptidase Fold
Zheng H, Miyakawa T, Sawano Y, Asano A, Okumura A, Yamagoe S, Tanokura M
Journal of Biological Chemistry. 2016 Aug 12;291(33):17133-42. Epub 2016 Jun 22.
doi: 10.1074/jbc.M116.720375.